TdB Labs is specialised in the development and manufacturing of dextran derivatives and other polysaccharides.

They offer fluorescent derivatives with FITC, TRITC, ATTO™-dyes and their proprietary Antonia Red™-dye.

Their non-fluorescent derivatives include e.g. different variants of dextran sulfate, including dextran sulfate sodium (DSS) for colitis.

 

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Dextran Sulfates

TdB Labs supplies two different series of dextran sulfates with either high- or low degree of sulfate substitution.

Their high substituted dextran sulfates contain 16-19% sulfate. Their low substituted dextran sulfates have a sulfur content of 8-13%.

The mean molecular weight of or dextran sulfates ranges from 5 kDa to 2000 kDa.

 

 

 

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Dextran sulfate sodium for colitis (DSS)

Dextran sulfate sodium (DSS) is the goldened standard for inducing colitis in experimental animals.

DSS is a dextran sulfate with a mean molecular with of 40 kDa and a sulfur content of 17-19 %.

About 40 years ago, TdB Labs was involved in the work that led to the development of colitis-grade DSS. 

 

 

 

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Blue dextrans

 Blue dextran from TdB Labs is labeled with Cibacron blue F3GA.

TdB Labs produces blue dextran with a mean molecular weight ranging from 5 kDa to 2000 kDa.