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HNL HOMODIMER ELISA Advances Biomarker for Sepsis Research |
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Neutrophil-specific biomarker you can trust. Detect sepsis early and monitor antibiotic response. |
| Mercodia’s HNL Homodimer ELISA provides a cutting-edge immunoassay designed to measure the neutrophil-specific homodimeric form of Human Neutrophil Lipocalin (HNL), also known as NGAL. This unique biomarker offers exceptional value for research on bacterial infections and antibiotic response in sepsis. |  |
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| What Makes HNL Homodimer UNIQUE |
| The homodimeric form of HNL is released exclusively from activated neutrophils during bacterial infection. This makes it a highly specific and fast-responding biomarker, offering earlier and more accurate insight into infection dynamics and treatment efficacy. |
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• Neutrophil- specific biomarker • Rapid response compared to CRP and PCT • Reflects real-time infection dynamic |
| Why HNL homodimer Matters in Sepsis Research |  |
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HNL is a glycoprotein stored in neutrophils and released upon activation. Its homodimeric form is uniquely neutrophil-specific, making it a precise indicator of infection-driven immune responses and antibiotic treatment success. By binding bacterial siderophores and limiting iron availability, HNL supports innate immunity, positioning the homodimeric form as a valuable biomarker for bacterial sepsis research. Common biomarkers such as C-reactive protein (CRP) and procalcitonin (PCT) lack specificity for neutrophil activation. They often respond slowly, show limited ability to distinguish bacterial from viral infections, and do not reliably track early antibiotic treatment effects. |
| Key Advantages with HNL Homodimer |
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• Highly specific, neutrophil-targeted biomarker • Rapid and reliable detection of bacterial infection • Superior to CRP and PCT for distinguishing bacterial vs viral infections • Sensitive monitoring of antibiotic response and disease progression • Supports early, evidence-based decision-making in sepsis |
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| Expert Insights Supporting HNL Homodimer |
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Technical Specification | |
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• Monoclonal-based sequential sandwich ELISA • 2h 15min incubation on 96-well plate • Measures homodimeric HNL with colorimetric detection • Sample volume: 5ul (EDTA Plasma) • Measurement range:0.039 - 5.0 ug/l • <0.1% cross-reactivity with EPX/EDN, ECP, EPO. Lysozyme, MPO |
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Ready to take your Sepsis Research Further? | |
| Explore HNL Homodimer ELISA |
